Chamblee54

The horse-dewormer circus moves right along. The media/government/google reaction is unchanged, even as more people find out inconvenient details. If you set the search parameters to 2018, before covid was a thing, you will see a few different things. Part one of this series is available.
Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to exceed expectations (15 February 2017) “Over the past decade, the global scientific community have begun to recognize the unmatched value of an extraordinary drug, ivermectin, that originates from a single microbe unearthed from soil in Japan. … Satoshi Ōmura … (received) the 2015 Nobel Prize in Physiology or Medicine, … with a collaborating partner … William Campbell, of Merck & Co. Today, ivermectin is continuing to surprise and excite scientists, offering more and more promise to help improve global public health by treating a diverse range of diseases, with its unexpected potential as an antibacterial, antiviral and anti-cancer agent being particularly extraordinary.” The news that Irish discoverer of Ivermectin jointly wins Nobel Prize for medicine was a surprise.
“The potential value of ivermectin in human medicine was not overlooked. I had always insisted that our written departmental objectives would include the development of new drugs for control of parasites in humans.” Apparently, IVM was initially developed for use in livestock. However, uses for humans started to emerge. It is unlikely that a single-use horse dewormer would win the Nobel Prize.
A key question in this discussion: Is Ivermectin safe for humans? This assumes that an appropriate dosage is administered. A 2018 report has one answer. The multitargeted drug ivermectin: from antiparasitic agent to repositioned cancer drug “In humans it is considered that ivermectin generates low levels of toxicity because its targets are confined within the CNS. Indeed, most patients treated with ivermectin have no side-effects other than those caused by the immune and inflammatory responses against the parasite, such as fever, pruritus, skin rashes and malaise , and when present, they appear within 24-48 h after treatment. Certainly, moderate symptoms … may be more related with the microfilarial load in the patient rather than with the intrinsic toxicity of ivermectin.”
“Like all medicines, this medicine can cause side effects, although not everybody gets them. Side effects are usually not serious and do not last long.” ~ “Is Ivermectin Safe? The short answer is yes. … Ivermectin is a drug well tolerated by humans, but this doesn’t mean that you can take it as if it were water. … it’s still medicine, and you should be very careful (with any drug) … There are side effects that can include headache, muscle aches; dizziness; nausea, diarrhea; or mild skin rash. … .”
So what is the appropriate dosage? You have to dig a bit to find out. As always, a medical professional should make the call on dosage. (Can a physician be trusted to give a good answer, seeing the pressure to use another treatment?) “… Stromectol may be used alone or with other medications. … “Dosage Guidelines for STROMECTOL (ivermectin) for Strongyloidiasis. The chart shows a proper dose, in 3 mg tablete, per body weight. 15-24 kg – 1 tablet, 25-35 kg – 2 tablets, 36-50 kg – 3 tablets, 51-65 kg – 4 tablets, 66-79 kg – 5 tablets, ≥ 80 kg – 200 mcg/kg.”
Doctor/patient trust is taking a beating. Physicians are apparently under pressure not to prescribe IVM. These trust issues also extend to the media. These two headlines are typical. Rand Paul has a *very* wacky theory about ivermectin Clamoring for ivermectin, some turn to a pro-Trump telemedicine website Even Fox News is playing along. Joe Rogan treats COVID-19 with ivermectin – but FDA, CDC warn against its use for coronavirus. When you have pharmaceutical advertisers, you do as you are told. (This rant by Rachel Maddow is noteworthy.)
Joe Rogan Says He Has COVID, Is Taking Ivermectin “I feel great,” the host declared, unconvincingly. … Joe Rogan, the UFC commentator and podcast host, has come down with COVID-19, he announced on Instagram. He said he’s treating the illness with, among other things, ivermectin, the unproven treatment beloved by anti-vaccine activists and right-wing politicians.” The big news this week is Joe Rogan using IVM to treat covid. Joe is well connected for illicit substances, and probably does not go to a feed store. The media reaction has been about what you expect.
@DRobertaLacerda “This is…unexpected… Tokyo’s Medical Associate Chairman holds live press conference recommending #ivermectin to all doctors, for all Covid patients. Japan’s government is one of the most conservative and cautious in the world. Data is clear Huge news.” When you ask google for more information, you are sent to reddit. “Are you sure you want to view this community? This community is quarantined: For medical advice, please consult your physician. Additional resources available at the Centers for Disease Control and Prevention. Are you certain you want to continue?” Pictures today are from The Library of Congress.